A number of medicinal, pharmaceutical and bioscience research studies
have developed therapies and tried to find diverse kinds of therapeutic
measures. However, no therapies could definitively treat rhinitis. But this
rhinitis can be quickly treated. Do not change the
intestinal tract but just change. It’s
the innovation using the concept of cell science and bioscience through a
series of continuing research projects. Rhinitis is more easily treated than a
cold. The fundamental cause of allergy, atopy or rhinitis is that the immune
system of the intestinal tract is distorted, not the skin or inside the skin. Allergy is defined as
conventional Th2 type inflammatory
disease. This is because the Th2 immune response plays an important role in
stimulating allergies. Allergens, the
antigen, flow into the body through the nasal cavity, skin or intestinal tract
and the antigen-presenting cell in the skin is recognized, to which the body
then reacts. At this point, the
allergen specifically prompts Th2 type
immune response and the cytokine of the Th2 type is expressed, accelerating the
secretion of histamine and production of IgE. The IgE antibody is
the immune globulin engaged in the occurrence of allergic diseases. The LgE
antibody is measured in the case of seborrheic dermatitis, allergic diseases,
atopy, asthma or rhinitis. → The IgA antibody is required in the body for
reducing IgE antibodies (for treating allergies). For treating allergic dermatitis and rhinitis, Lactobacillus Plantarum
K-1(LK-1) from Kimchi, the bacteria flora, is very effective to induce the IgA
antibody. When the immune system of the intestinal tract
is regulated, allergic diseases including rhinitis, itching and hypersensitive
activity including allergic diseases will be treated at once. (Features showing the treatment of allergic dermatitis having the same
cause as rhinitis as the immune system of intestinal tract) Our
body comprises a massive bacteria forest. While we are alive, bacteria
ceaselessly fight to expand their power. The bacterial flora keeps changing and
can’t help being destroyed. We always have to compete against others from
right when we wake up. We are always surrounded by stress, fatigue and overwork
and the conditions of the intestines can’t help being sensitive to this. The
proliferation of harmful bacteria reduces autoimmune antibodies and we are
exposed to allergic diseases. In this civilized age, we suffer from allergic
rhinitis. Allergic rhinitis is the hypersensitive reaction of nasal mucosa
against a specific substance. It’s an allergic disease characterized by
continuing sneeze, running clear nose (watery rhinorrhea) and nasal stuffiness
(rhinanchone). When our intestines are healthy, allergic rhinitis is resolved. The stomach is known as the digestive system. It is a very important
digestive organ because it is the immune system as well as the second brain. A
variety of bacteria enter the stomach while digesting various kinds of food. In
that process, immune activity is dynamically implemented. When the immune system is regulated, rhinitis is treated, cell functions
are restored and we can be free from intestinal tract diseases and skin
diseases. Rhinitis! Do not treat the inside of the nose. The cause of rhinitis is the immune system of the intestinal tract not
the inside of the nose. Powerful lactobacilli accelerate the generation of the IgA antibody in
the intestines. I also suffered from ceaseless sneezing and running nose. I was
completely restored after taking Lactobacillus Plantarum K-1, the lactobacilli
from Kimchi. Lactobacilli regulate the immune system of our intestinal tract
and heal allergic diseases including rhinitis and itching at once. Rhinitis and allergy are caused by the excessive formation and quantities
of the antibody IgE in the immune system if the intestinal tract becomes
unbalanced. There is no exposure to various kinds of infections
from when we are young because the environment is hygienically improved as
compared to the past. However, exposure to heavy metals due to pollution or
pesticides has been increasing and the ratio of patients complaining of
allergic symptoms including atopy and rhinitis has also been increasing. Rhinitis, allergy and atopy symptoms are caused by extreme immune
reaction. The IgE type antibody is related to about 70 to 80% of allergy
symptoms. The IgE antibody was originally for preventing parasites and is the
immunological allergic reaction generated against non-infective foreign
substances (including pollen, dust), accompanied by inflammation For patients with
allergic symptoms including itching and rhinitis, the Tred cell producing
TGF-beta withers and finally reduces the generation of IgA. This has now been
verified through clinical tests. It
is widely known that the powerful lactobacilli, LK-1(Lactobacillus Plantarum
K-1) of Bio Rhythm, keeps intestines healthy by normalizing the microflora
distorted for various reasons inside the intestines and stimulating the balance of
antibodies in the immune system of the intestinal tract. In other words, powerful lactobacilli help to inhibit infection of the
intestines by stimulating immune reaction (IL-10 and TGF-b) against infectious
microorganisms penetrating the intestines and producing IgA antibodies and
anti-microbial substances. The results indicate that powerful live Kimchi
lactobacilli can inhibit allergy and rhinitis. For rhinitis, fundamental treatment is important. When we lose the
balance of our immune system, allergy, atopy, itching or rhinitis occur. We could
manage such symptoms in the past since antibodies against antigens from nature
including the soil, plant, air or water were built when we freely came in
contact with nature. However, a number of scientists have found that allergy,
atopy or itching were caused as the immune system, the most important
controller in the intestines, lost its balance because we live in a fixed
environment--in other words, civilized society--with less opportunity to be in
contact with nature. Good news for atopy and rhinitis. Successful
treatment cases have been ongoing. -See the following- The dry
skin of patients suffering from atopic dermatitis and rhinitis increases
itching more than twice and makes skin vulnerable to infection. Ceramides
on the epidermis help skin to hold moisture. Those who suffer from atopic
dermatitis have less ceramides in the skin than healthy people. Their skin
lacks the enzyme for generating ceramide. This is because of abnormal ceramide
synthesis and bacterial infection. The precursor of ceramide is made but not
the ceramide itself.
The allergen is the causative substance causing allergy. It is accompanied by
severe itching. Lactobacilli control macrophages killing pathogens penetrating
from the outside. Macrophages prevent allergies by controlling T
cell-generating antibodies and killing viruses or cancer cells.
Lactobacilli were orally
administered to children suffering from atopic dermatitis. The interferon gamma
secretion was increased. This inhibited the secretion of cytokine increasing
antibodies causing allergy. Interlukin-4 is also a kind of cytokine including
the production of antibodies (IgE) causing allergies.
Accordingly,
it is necessary to inhibit secretion of interlukin-4 to eliminate allergies.
The secretion of interlukin-4 was inhibited by powerful lactobacilli. (Source: Lactobacilli making fermented food saved me.
Pyeonaem.The first impression of first edition printed on July 1, 2007.) Lactobacillus
Plantarum k-1 of Bio Rhythm, powerful Kimchi lactobacilli of Bio Rhythm coated
in 3 steps, improves and treats diseases including allergic disease, atopic
dermatitis, rhinitis and itching.
-Summary - L. plantarum K-1(LP), the lactobacillus inhibiting the activation of AP-1
and NF-ΚB, was separated from Kimchi and applied to mice to identify the
inhibitory activity against itching and hypersensitivity of the skin. LP
significantly activated NF-κB and c-jun, the
transcription factors, in the RBL-2H3 cell (rat basophilic leukemia) stimulated
by phorbol 12'-myristate 13'-acetate (PMA) and inhibited the expression of TNF-α
and IL-4. Furthermore, LP demonstrated strong inhibition
effects against positive hypersensitivity of the skin induced in mice by
IgE-antigen. When LP was administered to mice, 1x1010 per mouse, the
hypersensitivity of the mice was inhibited by up to 87.5%. When LP was
administered to mice, 1×1010 CFU per mouse, itching
induced by histamine was inhibited by up to 58.9%. LP substantially inhibited
osmosis into the blood caused by histamines. The effect was directly
proportionate to the effect inhibiting itching. LP ( 1×1010
CFU) inhibited the expression of IL-4, IL-1β and TNF-α
caused by histamines by 88.9%, 88.6% and 98.9%, respectively.
LP inhibited IgE induced by histamines by 85.3%. As a result, LP demonstrated
anti-allergic effects by controlling the expression of the IgE-switching
cytokine IL-4, proinflammatory cytokines IL- 1β and TNF-α
by inhibiting the activation of NF κB and
AP-1, the transcription factors in the immune cells, and treated diseases
including allergic diseases, atopic dermatitis, rhinitis and itching. Lactobacillus Plantarum k-1 of Bio Rhythm is a
remarkable product winning the Commissioner’s Prize of the Korean Intellectual Property Office in
the Korea Invention Patent Exhibition, and the Technology Innovation Prize from
the Small and Medium Enterprise Innovation Association of Korea. Its remarkable function is noticeable 2 weeks at the
latest after taking it when treatment starts. High-tech
bioengineering has been significantly advanced up to now. The following are
quoted from recently published international journals. Modern science caught it through the joint research. Do not treat the inside of the nose. Completely treat rhinitis and skin diseases by activating
the immune system of the intestinal tract and restoring the balance of
antibodies inside the nasal cavity.
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